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Citrate – technical card
THE LITHOGENIC RISK
HYPOCITRATURIA AND NEPHROLITHIASIS
One of the most frequent metabolic disorders in calcium nephrolithiasis is undoubtedly the Hypocitraturia, which occurs in 19-63% of patients.
The Hypocitraturia is today considered the main and most easily correctable cause of oxalocalcic kidney stones and citrate is the urinary inhibitor more easily evaluated and modulated by therapeutic intervention.
NORMAL LEVELS OF CITRATE AND HYPOCITRATURIA
The normal range of serum citrate is 13-28 mg / l, with an average of 20 mg / l. The normal levels of urinary citrate vary in the adult from 320 to 1260 mg/24 h with an average of 550 male and 680 female. The increased excretion of citrate in women is related to estrogen level and this could be the most important explanation for the lower incidence of kidney stones in women.
Download the Technical Card >>
HYPOCITRATURIA AND NEPHROLITHIASIS
One of the most frequent metabolic disorders in calcium nephrolithiasis is undoubtedly the Hypocitraturia, which occurs in 19-63% of patients.
The Hypocitraturia is today considered the main and most easily correctable cause of oxalocalcic kidney stones and citrate is the urinary inhibitor more easily evaluated and modulated by therapeutic intervention.
NORMAL LEVELS OF CITRATE AND HYPOCITRATURIA
The normal range of serum citrate is 13-28 mg / l, with an average of 20 mg / l. The normal levels of urinary citrate vary in the adult from 320 to 1260 mg/24 h with an average of 550 male and 680 female. The increased excretion of citrate in women is related to estrogen level and this could be the most important explanation for the lower incidence of kidney stones in women.
Download the Technical Card >>
